CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.40 | ATPase, nucleotide binding domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.420.40 |
| Functional Family | Hexokinase-1 |
Enzyme Information
| 2.7.1.1 |
Hexokinase.
based on mapping to UniProt P19367
ATP + D-hexose = ADP + D-hexose 6-phosphate.
-!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors. -!- ITP and dATP can act as donors.
|
UniProtKB Entries (1)
| P19367 |
HXK1_HUMAN
Homo sapiens
Hexokinase-1
|
PDB Structure
| PDB | 4FPB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Inhibitor Sites of Unequal Affinity Linked by Binding Synergism in Mutant Forms of Recombinant Human Hexokinase Type-I
to be published
|