CATH Domain 4flbA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.90

Domain Context

CATH Clusters

Superfamily	1.25.40.90
Functional Family	regulation of nuclear pre-mRNA domain-containing protein 2 isoform X1

Enzyme Information

UniProtKB Entries (1)

RPRD2_HUMAN

Homo sapiens

Regulation of nuclear pre-mRNA domain-containing protein 2

PDB Structure

PDB	4FLB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Ni, Z., Xu, C., Guo, X., Hunter, G.O., Kuznetsova, O.V., Tempel, W., Marcon, E., Zhong, G., Guo, H., Kuo, W.H., Li, J., Young, P., Olsen, J.B., Wan, C., Loppnau, P., El Bakkouri, M., Senisterra, G.A., He, H., Huang, H., Sidhu, S.S., Emili, A., Murphy, S., Mosley, A.L., Arrowsmith, C.H., Min, J., Greenblatt, J.F. Nat.Struct.Mol.Biol.