CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.90 | Cystine Knot Cytokines, subunit B |
|
2.10.90.10 | Cystine-knot cytokines |
Domain Context
CATH Clusters
| Superfamily | Cystine-knot cytokines |
| Functional Family | Brain-derived neurotrophic factor |
Enzyme Information
UniProtKB Entries (1)
| P01138 |
NGF_HUMAN
Homo sapiens
Beta-nerve growth factor
|
PDB Structure
| PDB | 4EDX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs
|
