CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.730 | Isoleucyl-tRNA Synthetase; Domain 1 |
|
1.10.730.10 | Isoleucyl-tRNA Synthetase; Domain 1 |
Domain Context
CATH Clusters
| Superfamily | Isoleucyl-tRNA Synthetase; Domain 1 |
| Functional Family | Leucine--tRNA ligase |
Enzyme Information
| 6.1.1.4 |
Leucine--tRNA ligase.
based on mapping to UniProt P07813
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).
|
UniProtKB Entries (1)
| P07813 |
SYL_ECOLI
Escherichia coli K-12
Leucine--tRNA ligase
|
PDB Structure
| PDB | 4CQN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Physiological Target for Leurs Translational Quality Control is Norvaline
Embo J.
|