CATH Domain 4c99D00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.220	Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2
	2.10.220.10	Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily	Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
Functional Family	R-spondin 4

Enzyme Information

UniProtKB Entries (1)

ZNRF3_MOUSE

Mus musculus

E3 ubiquitin-protein ligase ZNRF3

PDB Structure

PDB	4C99
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin. Zebisch, M., Xu, Y., Krastev, C., Macdonald, B.T., Chen, M., Gilbert, R.J.C., He, X., Jones, E.Y. Nat.Commun.