1 keywords

CATH Domain 4bd2A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.437 Apoptosis Regulator Bcl-x
Homologous Superfamily 1.10.437.10 Blc2-like

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family apoptosis regulator BAX isoform X2

Enzyme Information

UniProtKB Entries (1)

Q07812
BAX_HUMAN
Homo sapiens
Apoptosis regulator BAX

PDB Structure

PDB 4BD2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Czabotar, P.E., Westphal, D., Dewson, G., Ma, S., Hockings, C., Fairlie, W.D., Lee, E.F., Yao, S., Robin, A.Y., Smith, B.J., Huang, D.C., Kluck, R.M., Adams, J.M., Colman, P.M.
Cell(Cambridge,Mass.)