CATH Domain 4aqhB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Plasminogen activator inhibitor 1

Enzyme Information

UniProtKB Entries (1)

PAI1_HUMAN

Homo sapiens

Plasminogen activator inhibitor 1

PDB Structure

PDB	4AQH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation Fjellstrom, O., Deinum, J., Sjogren, T., Johansson, C., Geschwindner, S., Nerme, V., Legnehed, A., Mcpheat, J., Olsson, K., Bodin, C., Panuovic, A., Gustafsson, D. J.Biol.Chem.