CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family |
Enzyme Information
| 4.1.1.15 |
Glutamate decarboxylase.
based on mapping to UniProt Q99259
L-glutamate = 4-aminobutanoate + CO(2).
-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.
|
UniProtKB Entries (1)
| Q99259 |
DCE1_HUMAN
Homo sapiens
Glutamate decarboxylase 1
|
PDB Structure
| PDB | 3VP6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
Biosci.Rep.
|