CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.830 |
Domain Context
CATH Clusters
| Superfamily | 2.60.120.830 |
| Functional Family | ADAM metallopeptidase with thrombospondin type 1 motif 13 |
Enzyme Information
| 3.4.24.87 |
ADAMTS13 endopeptidase.
based on mapping to UniProt Q76LX8
The enzyme cleaves the von Willebrand factor at bond 842-Tyr-|-Met-843 within the A2 domain.
-!- Belongs to peptidase family M12.
|
UniProtKB Entries (1)
| Q76LX8 |
ATS13_HUMAN
Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 13
|
PDB Structure
| PDB | 3VN4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural analysis and biochemical studies of ADAMTS13 P475S mutant
To be Published
|