CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1600 | SIR2/SIRT2 'Small Domain' |
|
3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
| Superfamily | SIR2/SIRT2 'Small Domain' |
| Functional Family | NAD-dependent protein deacylase |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt Q8IE47
|
UniProtKB Entries (2)
| Q8IE47 |
SIR5_PLAF7
Plasmodium falciparum 3D7
NAD-dependent protein deacylase Sir2A
|
| P68431 |
H31_HUMAN
Homo sapiens
Histone H3.1
|
PDB Structure
| PDB | 3U3D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine
Acs Chem.Biol.
|