CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1410 | set domain protein methyltransferase, domain 1 |
|
3.90.1410.10 | set domain protein methyltransferase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | set domain protein methyltransferase, domain 1 |
| Functional Family | histone-lysine N-methyltransferase setd3 isoform X1 |
Enzyme Information
| 2.1.1.85 |
Protein-histidine N-methyltransferase.
based on mapping to UniProt Q86TU7
S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N(tau)-methyl-L-histidine.
-!- Highly specific for histidine residues, for example, in actin.
|
UniProtKB Entries (1)
| Q86TU7 |
SETD3_HUMAN
Homo sapiens
Actin-histidine N-methyltransferase
|
PDB Structure
| PDB | 3SMT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of human SET domain-containing protein3
To be Published
|