CATH Domain 3sdjK01

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.200	Phosphorylase Kinase; domain 1
	3.30.200.20	Phosphorylase Kinase; domain 1

Domain Context

CATH Clusters

Superfamily	Phosphorylase Kinase; domain 1
Functional Family	Serine/threonine-protein kinase/endoribonuclease IRE1

Enzyme Information

3.1.26.-	Endoribonucleases producing 5'-phosphomonoesters. based on mapping to UniProt P32361
2.7.11.1	Non-specific serine/threonine protein kinase. based on mapping to UniProt P32361 ATP + a protein = ADP + a phosphoprotein. -!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

IRE1_YEAST

Saccharomyces cerevisiae S288C

Serine/threonine-protein kinase/endoribonuclease IRE1

PDB Structure

PDB	3SDJ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and functional basis for RNA cleavage by Ire1. Korennykh, A.V., Korostelev, A.A., Egea, P.F., Finer-Moore, J., Stroud, R.M., Zhang, C., Shokat, K.M., Walter, P. Bmc Biol.