CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.605 | Aldehyde Dehydrogenase; Chain A, domain 1 |
|
3.40.605.10 | Aldehyde Dehydrogenase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Aldehyde Dehydrogenase; Chain A, domain 1 |
| Functional Family | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
Enzyme Information
| 1.5.1.6 |
Formyltetrahydrofolate dehydrogenase.
based on mapping to UniProt P28037
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
|
UniProtKB Entries (1)
| P28037 |
AL1L1_RAT
Rattus norvegicus
Cytosolic 10-formyltetrahydrofolate dehydrogenase
|
PDB Structure
| PDB | 3RHJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem.
|
