CATH Classification

Domain Context

CATH Clusters

Superfamily Superoxide dismutase, copper/zinc binding domain
Functional Family Superoxide dismutase [Cu-Zn]

Enzyme Information

1.15.1.1
Superoxide dismutase.
based on mapping to UniProt P00441
2 superoxide + 2 H(+) = O(2) + H(2)O(2).

UniProtKB Entries (1)

P00441
SODC_HUMAN
Homo sapiens
Superoxide dismutase [Cu-Zn]

PDB Structure

PDB 3QQD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R.
Seetharaman, S.V., Winkler, D.D., Taylor, A.B., Cao, X., Whitson, L.J., Doucette, P.A., Valentine, J.S., Schirf, V., Demeler, B., Carroll, M.C., Culotta, V.C., Hart, P.J.
Biochemistry
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