CATH Classification
Domain Context
CATH Clusters
| Superfamily | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
| Functional Family | Phosphodiesterase 9A |
Enzyme Information
| 3.1.4.35 |
3',5'-cyclic-GMP phosphodiesterase.
based on mapping to UniProt O76083
Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.
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UniProtKB Entries (1)
| O76083 |
PDE9A_HUMAN
Homo sapiens
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
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PDB Structure
| PDB | 3QI3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine.
Plos One
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