CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family glutaminyl-peptide cyclotransferase-like protein

Enzyme Information

2.3.2.5
Glutaminyl-peptide cyclotransferase.
based on mapping to UniProt Q9NXS2
L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH(3).
-!- Involved in the formation of thyrotropin-releasing hormone and other biologically active peptides containing N-terminal pyroglutamyl residues. -!- The enzyme from papaya also acts on glutaminyl-tRNA.

UniProtKB Entries (1)

Q9NXS2
QPCTL_HUMAN
Homo sapiens
Glutaminyl-peptide cyclotransferase-like protein

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
CATH-Gene3D is a Global Biodata Core Resource Learn more...