CATH Classification

Domain Context

CATH Clusters

Superfamily Galactose-binding domain-like
Functional Family Ephrin type-B receptor 2

Enzyme Information

2.7.10.1
Receptor protein-tyrosine kinase.
based on mapping to UniProt P54753
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P54753
EPHB3_HUMAN
Homo sapiens
Ephrin type-B receptor 3

PDB Structure

PDB 3P1I
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ligand Binding Domain of Human Ephb3
Walker, J.R., Yermekbayeva, L., Seitova, A., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.
To be Published