CATH Domain 3o8oH04

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.460	Phosphofructokinase domain

Domain Context

CATH Clusters

Superfamily	Phosphofructokinase domain
Functional Family	ATP-dependent 6-phosphofructokinase

Enzyme Information

2.7.1.11

6-phosphofructokinase.

based on mapping to UniProt P16862

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.

-!- D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors. -!- UTP, CTP and ITP can act as donors. -!- Not identical with EC 2.7.1.105.

UniProtKB Entries (1)

P16862

PFKA2_YEAST

Saccharomyces cerevisiae S288C

ATP-dependent 6-phosphofructokinase subunit beta

PDB Structure

PDB	3O8O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Crystal Structures of Eukaryotic Phosphofructokinases from Baker's Yeast and Rabbit Skeletal Muscle. Banaszak, K., Mechin, I., Obmolova, G., Oldham, M., Chang, S.H., Ruiz, T., Radermacher, M., Kopperschlager, G., Rypniewski, W. J.Mol.Biol.