CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1190.20
Functional Family Ketohexokinase

Enzyme Information

2.7.1.3
Ketohexokinase.
based on mapping to UniProt P50053
ATP + D-fructose = ADP + D-fructose 1-phosphate.
-!- D-sorbose, D-agatose and 5-dehydro-D-fructose also act as acceptors.

UniProtKB Entries (1)

P50053
KHK_HUMAN
Homo sapiens
Ketohexokinase

PDB Structure

PDB 3NC9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Electron density guided fragment-based lead discovery of ketohexokinase inhibitors.
Gibbs, A.C., Abad, M.C., Zhang, X., Tounge, B.A., Lewandowski, F.A., Struble, G.T., Sun, W., Sui, Z., Kuo, L.C.
J.Med.Chem.
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