CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.12350
Functional Family Eyes absent homolog

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt O00167
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

O00167
EYA2_HUMAN
Homo sapiens
Eyes absent homolog 2

PDB Structure

PDB 3HB1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Jung, S.K., Jeong, D.G., Chung, S.J., Kim, J.H., Park, B.C., Tonks, N.K., Ryu, S.E., Kim, S.J.
Faseb J.