CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.170 | Formyl transferase, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Formyl transferase, N-terminal domain |
| Functional Family | Phosphoribosylglycinamide formyltransferase |
Enzyme Information
| 2.1.2.2 |
Phosphoribosylglycinamide formyltransferase.
based on mapping to UniProt P9WHM5
10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
|
UniProtKB Entries (1)
| P9WHM5 |
PUR3_MYCTU
Mycobacterium tuberculosis H37Rv
Phosphoribosylglycinamide formyltransferase
|
PDB Structure
| PDB | 3DCJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
J.Mol.Biol.
|
