CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family Poly(A)-specific ribonuclease PARN

Enzyme Information

3.1.13.4
Poly(A)-specific ribonuclease.
based on mapping to UniProt Q8VDG3
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.

UniProtKB Entries (1)

Q8VDG3
PARN_MOUSE
Mus musculus
Poly(A)-specific ribonuclease PARN

PDB Structure

PDB 3D45
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.
Wu, M., Nilsson, P., Henriksson, N., Niedzwiecka, A., Lim, M.K., Cheng, Z., Kokkoris, K., Virtanen, A., Song, H.
Structure