CATH Domain 3curJ00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.645	Cytochrome-c3 Hydrogenase; chain B
	1.10.645.10	Cytochrome-c3 Hydrogenase, chain B

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 Hydrogenase, chain B
Functional Family	Hydrogenase 2 large subunit

Enzyme Information

1.12.2.1

Cytochrome-c3 hydrogenase.

based on mapping to UniProt P18188

H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.

-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P18187

PHNS_DESFR

Desulfovibrio fructosivorans

Periplasmic [NiFe] hydrogenase small subunit

PDB Structure

PDB	3CUR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Experimental approaches to kinetics of gas diffusion in hydrogenase Leroux, F., Dementin, S., Burlat, B., Cournac, L., Volbeda, A., Champ, S., Martin, L., Guigliarelli, B., Bertrand, P., Fontecilla-Camps, J., Rousset, M. Proc.Natl.Acad.Sci.Usa