CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.506 | GTPase Activation - p120GAP; domain 1 |
|
1.10.506.10 | GTPase Activation - p120gap; domain 1 |
Domain Context
CATH Clusters
| Superfamily | GTPase Activation - p120gap; domain 1 |
| Functional Family | Ras GTPase-activating protein nGAP isoform 2 |
Enzyme Information
UniProtKB Entries (1)
| Q9QUH6 |
SYGP1_RAT
Rattus norvegicus
Ras/Rap GTPase-activating protein SynGAP
|
PDB Structure
| PDB | 3BXJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
Embo Rep.
|