1 keywords

CATH Domain 3bg3A05

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.50 OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous Superfamily 2.40.50.100 RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain

Domain Context

CATH Clusters

Superfamily 2.40.50.100
Functional Family Acetyl-CoA carboxylase biotin carboxyl carrier protein

Enzyme Information

6.4.1.1
Pyruvate carboxylase.
based on mapping to UniProt P11498
ATP + pyruvate + HCO(3)(-) = ADP + phosphate + oxaloacetate.
-!- The animal enzyme requires acetyl-CoA.

UniProtKB Entries (1)

P11498
PYC_HUMAN
Homo sapiens
Pyruvate carboxylase, mitochondrial

PDB Structure

PDB 3BG3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.
Xiang, S., Tong, L.
Nat.Struct.Mol.Biol.