CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Protein-tyrosine sulfotransferase |
Enzyme Information
| 2.8.2.20 |
Protein-tyrosine sulfotransferase.
based on mapping to UniProt O60704
3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
-!- The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors. -!- Formerly EC 2.8.2.n1.
|
UniProtKB Entries (1)
| O60704 |
TPST2_HUMAN
Homo sapiens
Protein-tyrosine sulfotransferase 2
|
PDB Structure
| PDB | 3AP1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of human tyrosylprotein sulfotransferase-2 reveals the mechanism of protein tyrosine sulfation reaction.
Nat Commun
|
