CATH Classification
Domain Context
CATH Clusters
| Superfamily | Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A |
| Functional Family | Histo-blood group ABO system transferase |
Enzyme Information
| 2.4.1.87 |
N-acetyllactosaminide 3-alpha-galactosyltransferase.
based on mapping to UniProt P14769
UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D- glucosaminyl-R = UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl- (1->4)-beta-N-acetylglucosaminyl-R.
-!- Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo- alpha(1)-acid glycoprotein and N-acetyllactosamine (beta-D- galactosyl-1,4-N-acetyl-beta-D-glucosamine), but not on 2'-fucosylated-N-acetyllactosamine. -!- The non-reducing terminal N-acetyllactosamine residues of glycoproteins can also act as acceptor. -!- Formerly EC 2.4.1.124 and EC 2.4.1.151.
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UniProtKB Entries (1)
| P14769 |
GGTA1_BOVIN
Bos taurus
N-acetyllactosaminide alpha-1,3-galactosyltransferase
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PDB Structure
| PDB | 2WGZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Alpha-1,3 Galactosyltransferase (Alpha3Gt) in a Complex with P-Nitrophenyl-Beta-Galactoside (Pnpbetagal).
Biochem.Biophys.Res.Commun.
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