CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.140 | Nucleic acid-binding proteins |
Domain Context
CATH Clusters
| Superfamily | Nucleic acid-binding proteins |
| Functional Family | 23S rRNA (uracil(747)-C(5))-methyltransferase |
Enzyme Information
| 2.1.1.35 |
tRNA (uracil(54)-C(5))-methyltransferase.
based on mapping to UniProt Q9UZR7
S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54) in tRNA.
-!- Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate and FADH(2) to supply the atoms for methylation of U54.
|
UniProtKB Entries (1)
| Q9UZR7 |
ATRMA_PYRAB
Pyrococcus abyssi GE5
TRNA (uracil(54)-C(5))-methyltransferase
|
PDB Structure
| PDB | 2VS1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.
Nucleic Acids Res.
|
