CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Nicotinamide riboside kinase 1 |
Enzyme Information
| 2.7.1.173 |
Nicotinate riboside kinase.
based on mapping to UniProt Q9NWW6
ATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide.
-!- The enzyme from yeast and human also has the activity of EC 2.7.1.22. -!- Formerly EC 2.7.1.n4.
|
| 2.7.1.22 |
Ribosylnicotinamide kinase.
based on mapping to UniProt Q9NWW6
ATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide.
|
UniProtKB Entries (1)
| Q9NWW6 |
NRK1_HUMAN
Homo sapiens
Nicotinamide riboside kinase 1
|
PDB Structure
| PDB | 2QG6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human nicotinamide riboside kinase
Structure
|
