CATH Domain 2qepB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.190	Protein-Tyrosine Phosphatase; Chain A
	3.90.190.10	Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily	Protein tyrosine phosphatase superfamily
Functional Family	receptor-type tyrosine-protein phosphatase-like N isoform X2

Enzyme Information

3.1.3.48	Protein-tyrosine-phosphatase. based on mapping to UniProt Q92932 Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
3.1.3.-	Phosphoric monoester hydrolases. based on mapping to UniProt Q92932

UniProtKB Entries (1)

PTPR2_HUMAN

Homo sapiens

Receptor-type tyrosine-protein phosphatase N2

PDB Structure

PDB	2QEP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr, A.J., Ugochukwu, E., Lee, W.H., King, O.N., Filippakopoulos, P., Alfano, I., Savitsky, P., Burgess-Brown, N.A., Muller, S., Knapp, S. Cell(Cambridge,Mass.)