CATH Domain 2pw6A00

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.830	Protocatechuate 4,5-dioxygenase; Chain B
	3.40.830.10	LigB-like

Superfamily	LigB-like
Functional Family	4,5-DOPA dioxygenase extradiol

1.13.11.29

Stizolobate synthase.

based on mapping to UniProt P24197

L-dopa + O(2) = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.

-!- The intermediate product undergoes ring closure and oxidation, with NAD(P)(+) as acceptor, to stizolobic acid.

YGID_ECOLI

Escherichia coli K-12

4,5-DOPA dioxygenase extradiol

PDB	2PW6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12. Newton, M.G., Takagi, Y., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokayama, S., Li, Y., Chen, L., Zhu, J., Ruble, J., Liu, Z.J., Rose, J.P., Wang, B.-C. To be Published