CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.90 | Cystine Knot Cytokines, subunit B |
|
2.10.90.10 | Cystine-knot cytokines |
Domain Context
CATH Clusters
| Superfamily | Cystine-knot cytokines |
| Functional Family | Transforming growth factor beta |
Enzyme Information
UniProtKB Entries (1)
| P36897 |
TGFR1_HUMAN
Homo sapiens
TGF-beta receptor type-1
|
PDB Structure
| PDB | 2PJY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.
Mol.Cell
|