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1 keywords

CATH Domain 2nz6A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.190 Protein-Tyrosine Phosphatase; Chain A
Homologous Superfamily 3.90.190.10 Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Receptor-type tyrosine-protein phosphatase beta

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q12913
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q12913
PTPRJ_HUMAN
Homo sapiens
Receptor-type tyrosine-protein phosphatase eta

PDB Structure

PDB 2NZ6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Barr, A.J., Ugochukwu, E., Lee, W.H., King, O.N., Filippakopoulos, P., Alfano, I., Savitsky, P., Burgess-Brown, N.A., Muller, S., Knapp, S.
Cell(Cambridge,Mass.)
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