CATH Domain 2m8dB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily	3.30.70.330
Functional Family	Serine/arginine-rich splicing factor 1

Enzyme Information

UniProtKB Entries (1)

SRSF1_HUMAN

Homo sapiens

Serine/arginine-rich splicing factor 1

PDB Structure

PDB	2M8D
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition. Clery, A., Sinha, R., Anczukow, O., Corrionero, A., Moursy, A., Daubner, G.M., Valcarcel, J., Krainer, A.R., Allain, F.H. Proc.Natl.Acad.Sci.USA