CATH Classification

Domain Context

CATH Clusters

Superfamily S15/NS1, RNA-binding
Functional Family histidine--tRNA ligase, cytoplasmic isoform X6

Enzyme Information

6.1.1.21
Histidine--tRNA ligase.
based on mapping to UniProt P12081
ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).

UniProtKB Entries (1)

P12081
SYHC_HUMAN
Homo sapiens
Histidine--tRNA ligase, cytoplasmic

PDB Structure

PDB 2LW7
External Links
Method SOLUTION NMR
Organism
Primary Citation
NMR solution structure of human HisRS splice variant
Ye, F., Wei, Z., Wu, J., Schimmel, P., Zhang, M.
To be Published