CATH Classification

Domain Context

CATH Clusters

Superfamily Complement Module, domain 1
Functional Family Complement factor H

Enzyme Information

UniProtKB Entries (1)

P08603
CFAH_HUMAN
Homo sapiens
Complement factor H

PDB Structure

PDB 2JGX
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
Herbert, A.P., Deakin, J.A., Schmidt, C.Q., Blaum, B.S., Egan, C., Ferreira, V.P., Pangburn, M.K., Lyon, M., Uhrin, D., Barlow, P.N.
J. Biol. Chem.