CATH Classification

Domain Context

CATH Clusters

Superfamily RNA-binding S4 domain
Functional Family Pseudouridine synthase

Enzyme Information

5.4.99.23
23S rRNA pseudouridine(1911/1915/1917) synthase.
based on mapping to UniProt P33643
23S rRNA uridine(1911)/uridine(1915)/uridine(1917) = 23S rRNA pseudouridine(1911)/pseudouridine(1915)/pseudouridine(1917).
-!- Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines. -!- These nucleotides are located in the functionally important helix- loop 69 of 23S rRNA.

UniProtKB Entries (1)

P33643
RLUD_ECOLI
Escherichia coli K-12
Ribosomal large subunit pseudouridine synthase D

PDB Structure

PDB 2IST
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of RluD from E. coli
Foster, P.G., Finer-Moore, J.S., Stroud, R.M.
TO BE PUBLISHED
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