CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Phenylethanolamine N-methyltransferase

Enzyme Information

2.1.1.1
Nicotinamide N-methyltransferase.
based on mapping to UniProt P40261
S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide.

UniProtKB Entries (1)

P40261
NNMT_HUMAN
Homo sapiens
Nicotinamide N-methyltransferase

PDB Structure

PDB 2IIP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Crystal Structure of Human Nicotinamide N-methyltransferase in complex with SAH
Bernstein, G., Min, J., Wu, H., Tempel, W., Zeng, H., Loppnau, P., Avvakumov, G.V., Wasney, G., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N.
To be Published