CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.25 | Laminin |
|
2.10.25.10 | Laminin |
Domain Context
CATH Clusters
| Superfamily | Laminin |
| Functional Family | Urokinase-type plasminogen activator |
Enzyme Information
| 3.4.21.73 |
U-plasminogen activator.
based on mapping to UniProt P00749
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
-!- Formed from the inactive precursor by action of plasmin or plasma kallikrein. -!- Differs in structure from EC 3.4.21.68, and does not bind to fibrin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.21.31 and EC 3.4.99.26.
|
UniProtKB Entries (1)
| Q03405 |
UPAR_HUMAN
Homo sapiens
Urokinase plasminogen activator surface receptor
|
PDB Structure
| PDB | 2I9B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Drosophila |
| Primary Citation |
Structural basis of interaction between urokinase-type plasminogen activator and its receptor.
J.Mol.Biol.
|
