CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Cancer-related nucleoside-triphosphatase |
Enzyme Information
| 3.6.1.15 |
Nucleoside-triphosphate phosphatase.
based on mapping to UniProt Q9BSD7
NTP + H(2)O = NDP + phosphate.
-!- The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria. -!- Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD. -!- The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
|
UniProtKB Entries (1)
| Q9BSD7 |
NTPCR_HUMAN
Homo sapiens
Cancer-related nucleoside-triphosphatase
|
PDB Structure
| PDB | 2I3B |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
NMR Structure and Functional Characterization of a Human Cancer-related Nucleoside Triphosphatase.
J.Mol.Biol.
|
