CATH Domain 2hdxF00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.505	SHC Adaptor Protein
	3.30.505.10	SH2 domain

Domain Context

CATH Clusters

Superfamily	SH2 domain
Functional Family	SH2B adapter protein 1 isoform 2

Enzyme Information

UniProtKB Entries (1)

JAK2_MOUSE

Mus musculus

Tyrosine-protein kinase JAK2

PDB Structure

PDB	2HDX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. Hu, J., Hubbard, S.R. J.Mol.Biol.