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1 keywords

CATH Domain 2frxD01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.150 Vaccinia Virus protein VP39

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Ribosomal RNA small subunit methyltransferase F

Enzyme Information

2.1.1.178
16S rRNA (cytosine(1407)-C(5))-methyltransferase.
based on mapping to UniProt P76273
S-adenosyl-L-methionine + cytosine(1407) in 16S rRNA = S-adenosyl-L- homocysteine + 5-methylcytosine(1407) in 16S rRNA.
-!- The enzyme specifically methylates cytosine(1407) at C(5) in 16S rRNA.

UniProtKB Entries (1)

P76273
RSMF_ECOLI
Escherichia coli K-12
Ribosomal RNA small subunit methyltransferase F

PDB Structure

PDB 2FRX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain
Hallberg, B.M., Ericsson, U.B., Johnson, K.A., Andersen, N.M., Douthwaite, S., Nordlund, P., Beuscher IV, A.E., Erlandsen, H.
J.Mol.Biol.
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