CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.30 | Glutaredoxin | |
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
Superfamily | Glutaredoxin |
Functional Family | Glutathione peroxidase |
Enzyme Information
1.11.1.9 |
Glutathione peroxidase.
based on mapping to UniProt P07203
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
|
UniProtKB Entries (1)
P07203 |
GPX1_HUMAN
Homo sapiens
Glutathione peroxidase 1
|
PDB Structure
PDB | 2F8A |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
To be Published
|