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1 keywords

CATH Domain 2d7rA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Polypeptide N-acetylgalactosaminyltransferase

Enzyme Information

2.4.1.41
Polypeptide N-acetylgalactosaminyltransferase.
based on mapping to UniProt Q86SR1
(1) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine. (2) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine.
-!- The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.

UniProtKB Entries (1)

Q86SR1
GLT10_HUMAN
Homo sapiens
Polypeptide N-acetylgalactosaminyltransferase 10

PDB Structure

PDB 2D7R
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10)
Kubota, T., Shiba, T., Sugioka, S., Furukawa, S., Sawaki, H., Kato, R., Wakatsuki, S., Narimatsu, H.
J.Mol.Biol.
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