CATH Classification
Level | CATH Code | Description |
---|---|---|
4 | Few Secondary Structures | |
4.10 | Irregular | |
4.10.470 | Ricin (A Subunit), domain 2 | |
4.10.470.10 | Ricin (A Subunit), domain 2 |
Domain Context
CATH Clusters
Superfamily | Ricin (A Subunit), domain 2 |
Functional Family | Ricin |
Enzyme Information
3.2.2.22 |
rRNA N-glycosylase.
based on mapping to UniProt P02879
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.
|
UniProtKB Entries (1)
P02879 |
RICI_RICCO
Ricinus communis
Ricin
|
PDB Structure
PDB | 2AAI |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystallographic refinement of ricin to 2.5 A.
Proteins
|