CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | rRNA adenine N(6)-methyltransferase |
Enzyme Information
| 2.1.1.183 |
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase.
based on mapping to UniProt Q9UNQ2
4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)- dimethyladenine(1780) in 18S rRNA.
-!- DIM1 is involved in pre-rRNA processing. -!- Formerly EC 2.1.1.48.
|
UniProtKB Entries (1)
| Q9UNQ2 |
DIM1_HUMAN
Homo sapiens
Probable dimethyladenosine transferase
|
PDB Structure
| PDB | 1ZQ9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human Dimethyladenosine transferase with SAM
TO BE PUBLISHED
|
