CATH Domain 1ylkD00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1050	Beta-carbonic Anhydrase; Chain A
	3.40.1050.10	Carbonic anhydrase

Domain Context

CATH Clusters

Superfamily	Carbonic anhydrase
Functional Family	Beta-carbonic anhydrase 1

Enzyme Information

4.2.1.1

Carbonic anhydrase.

based on mapping to UniProt P9WPJ7

H(2)CO(3) = CO(2) + H(2)O.

-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P9WPJ7

MTCA1_MYCTU

Mycobacterium tuberculosis H37Rv

Beta-carbonic anhydrase 1

PDB Structure

PDB	1YLK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure and function of carbonic anhydrases from Mycobacterium tuberculosis. Suarez Covarrubias, A., Larsson, A.M., Hogbom, M., Lindberg, J., Bergfors, T., Bjorkelid, C., Mowbray, S.L., Unge, T., Jones, T.A. J.Biol.Chem.