CATH Domain 1ylcA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Anionic trypsin-2

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00763

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00763	TRY2_RAT Rattus norvegicus Anionic trypsin-2
P00974	BPT1_BOVIN Bos taurus Pancreatic trypsin inhibitor

PDB Structure

PDB	1YLC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin Getun, I.V., Brown, C.K., Tulla-Puche, J., Ohlendorf, D., Woodward, C., Barany, G. J.Mol.Biol.