CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.15 | Metallo-beta-lactamase; Chain A |
|
3.60.15.10 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
| Functional Family | Ribonuclease Z |
Enzyme Information
| 3.1.26.11 |
Ribonuclease Z.
based on mapping to UniProt P54548
Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
-!- No cofactor requirements.
|
UniProtKB Entries (1)
| P54548 |
RNZ_BACSU
Bacillus subtilis subsp. subtilis str. 168
Ribonuclease Z
|
PDB Structure
| PDB | 1Y44 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for substrate binding, cleavage and allostery in the tRNA maturase RNase Z.
Nature
|