CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family amyloid beta A4 precursor protein-binding family A member 1

Enzyme Information

UniProtKB Entries (1)

Q02410
APBA1_HUMAN
Homo sapiens
Amyloid-beta A4 precursor protein-binding family A member 1

PDB Structure

PDB 1X11
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
Zhang, Z., Lee, C.H., Mandiyan, V., Borg, J.P., Margolis, B., Schlessinger, J., Kuriyan, J.
EMBO J.